{"id":1414,"date":"2022-04-17T16:13:05","date_gmt":"2022-04-17T07:13:05","guid":{"rendered":"https:\/\/yobou.work\/?p=1414"},"modified":"2023-05-20T16:36:52","modified_gmt":"2023-05-20T07:36:52","slug":"%e3%83%95%e3%83%83%e5%8c%96%e7%89%a9%e3%83%90%e3%83%bc%e3%83%8b%e3%83%83%e3%82%b7%e3%83%a5%e3%81%ae%e5%8a%b9%e6%9e%9c%e3%81%a8%e5%ae%89%e5%85%a8%e6%80%a7%e3%80%80%ef%bd%9e%e3%81%86%e8%9d%95%e4%ba%88","status":"publish","type":"post","link":"https:\/\/yobou.work\/?p=1414","title":{"rendered":"\u3010\u30a8\u30d3\u30c7\u30f3\u30b9\u3011\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u52b9\u679c\u3068\u5b89\u5168\u6027\u3000\uff5e\u3046\u8755\u4e88\u9632\u306b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u6709\u52b9\u306a\u306e\u304b\uff5e"},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

\u30002020\u5e74\uff0c\u4e16\u754c\u7684\u306b\u5c55\u958b\u3055\u308c\u3066\u3044\u305f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u300c\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F(3M)\u300d\u304c\u65e5\u672c\u3067\u8ca9\u58f2\u958b\u59cb\u3068\u306a\u308a\uff0c\u7d9a\u3044\u30662021\u5e74\uff0c\u30a6\u30eb\u30c8\u30e9\u30c7\u30f3\u30c8\u304b\u3089\u3082\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u300c\u30a8\u30ca\u30e1\u30e9\u30b9\u30c8\u300d\u304c\u8ca9\u58f2\u958b\u59cb\u3068\u306a\u308a\u307e\u3057\u305f\uff0e<\/p>\n

\u3000\u5b9f\u306f\uff0c\u65e5\u672c\u306b\u304a\u3051\u308b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u6b74\u53f2\u306f\u53e4\u304f1981\u5e74\u306b\u767a\u58f2\u3055\u308c\u305f\u300cF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5(\u30d3\u30fc\u30d6\u30e9\u30f3\u30c9\u30e1\u30c7\u30a3\u30b3\u30fc\u30c7\u30f3\u30bf\u30eb\/\u6771\u6d0b\u88fd\u85ac\u5316\u6210)\u300d\u304c\u6700\u521d\u3067\u73fe\u5728\u3082\u8ca9\u58f2\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u6b8b\u5ff5\u306a\u304c\u3089F\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u5f8c\u767a\u54c1\u30671998\u5e74\u8ca9\u58f2\u958b\u59cb\u306e\u300c\u30c0\u30a4\u30e4\u30c7\u30f3\u30c8(\u662d\u548c\u85ac\u54c1\u5316\u5de5)\u300d\u306f2020\u5e74\u306b\u8ca9\u58f2\u4e2d\u6b62\u306b\u306a\u3063\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u9069\u5fdc\u306f\u3044\u305a\u308c\u3082\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3067\u3059\u304c\uff0c22,600ppm\u3068\u9ad8\u6fc3\u5ea6\u306e\u30d5\u30c3\u5316\u7269\u88fd\u5264\u3067\u3042\u308b\u3053\u3068\u304b\u3089\uff0c\u3046\u8755\u4e88\u9632\u5264\u3068\u3057\u3066\u6d3b\u7528\u3057\u3066\u3044\u308b\u6b6f\u79d1\u81e8\u5e8a\u533b\u3082\u591a\u304f\u3044\u307e\u3059\uff0e\u4eca\u56de\u306f\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u88fd\u5264\u3067\u3042\u308b\u300c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u300d\u306e\u3046\u8755\u4e88\u9632\u7528\u9014\u306b\u304a\u3051\u308b\u52b9\u679c\u3068\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u30d5\u30a9\u30fc\u30ab\u30b9\u3092\u5f53\u3066\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

 <\/p>\n

\uff11\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306b\u3064\u3044\u3066<\/h2>\n

(1)\u6982\u8981<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f22,600ppm\u306e\u30d5\u30c3\u5316\u30ca\u30c8\u30ea\u30a6\u30e0\u306b\u30ed\u30b8\u30f3(\u677e\u30e4\u30cb\uff0ccolophony)\uff0c\u30a8\u30bf\u30ce\u30fc\u30eb\u306a\u3069\u306e\u6eb6\u5a92\uff0c\u9999\u6599\u306a\u3069\u3092\u52a0\u3048\u305f\u30cd\u30d0\u30cd\u30d0\u3068\u3057\u305f\u88fd\u5264\u3067\u3059\uff0e\u6b6f\u9762\u306b\u5857\u5e03\u3055\u308c\u305f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u6642\u9593\u3068\u3068\u3082\u306b\u786c\u5316\u3057\uff0c\u8c61\u7259\u7d30\u7ba1\u5185\u3084\u6b6f\u8cea\u8868\u9762\u306b\u6790\u51fa\u3057\u305f\u30d5\u30c3\u5316\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u6301\u7d9a\u7684\u306b\u30d5\u30c3\u7d20\u30a4\u30aa\u30f3\u3092\u6b6f\u9762\u306b\u4f9b\u7d66\u3057\u307e\u3059\uff0e\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u5834\u5408\uff0c\u3053\u306e\u30d5\u30c3\u5316\u7269\u306e\u30b3\u30fc\u30c6\u30a3\u30f3\u30b0\u306b\u3088\u3063\u3066\u77e5\u899a\u904e\u654f\u3092\u6291\u5236\u3057\u307e\u3059\uff0e<\/p>\n

\"\"<\/p>\n

fig.1 \u7b46\u3067\u5857\u308a\u3084\u3059\u3044\u65b0\u3057\u3044\u4e16\u4ee3\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5(\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F)<\/p>\n

\u3000Duraphat(Colgate)\uff0cF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306a\u3069\u306e\u65e7\u6765\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3068\u7570\u306a\u308a\uff0c\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F(3M)\uff0c\u30a8\u30ca\u30e1\u30e9\u30b9\u30c8(\u30a6\u30eb\u30c8\u30e9\u30c7\u30f3\u30c8)\u306a\u3069\u306e\u65b0\u3057\u3044\u4e16\u4ee3\u306e\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5264\u306f\u767d\u8272\u3067\u67d4\u3089\u304b\u304f\uff0c\u30cd\u30d0\u4ed8\u304d\u304c\u6291\u3048\u3089\u308c\uff0c\u30c7\u30a3\u30b9\u30dd\u30fc\u30b6\u30d6\u30eb\u306e\u7b46\u306a\u3069\u3067\u6b6f\u9762\u5168\u4f53\u306b\u5857\u5e03\u3057\u3084\u3059\u3044\u8a2d\u8a08\u306b\u306a\u3063\u3066\u3044\u307e\u3059\uff0e\u307e\u305f\uff0c\u88fd\u5264\u3082\uff11\u56de\u4f7f\u7528\u91cf\u3054\u3068\u306b\u500b\u5305\u88c5\u3055\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n

(2)\u63a8\u5968\u3068\u9069\u5fdc<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f22,600ppm\u3068\u9ad8\u6fc3\u5ea6\u306a\u304c\u3089\u5b89\u5168\u6027\u304c\u9ad8\u3044\u305f\u3081\uff0c\u7c73\u56fd\u6b6f\u79d1\u533b\u5e2b\u4f1a(ADA)\uff0c\u7c73\u56fd\u5c0f\u5150\u6b6f\u79d1\u5b66\u4f1a\u306f\u3082\u3061\u308d\u3093\uff0c\u7c73\u56fd\u5c0f\u5150\u79d1\u5b66\u4f1a\u3082\u63a8\u5968\u3057\u3066\u3044\u308b1\uff09<\/sup>\u3088\u3046\u306b\u6210\u4eba\u306e\u307f\u306a\u3089\u305a\u4e73\u5150\u30fb\u5c0f\u5150\u306b\u5bfe\u3059\u308b\u3046\u8755\u6291\u5236\u76ee\u7684\u306b\u3082\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u7c73\u56fd\u3068\u82f1\u56fd\u3067\u306f\u65e5\u672c\u3068\u540c\u69d8\u306b\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u306e\u8a8d\u53ef\u3067\u3042\u308a\uff0c\u3046\u8755\u4e88\u9632\u306e\u305f\u3081\u306e\u8a8d\u53ef\u306f\u53d7\u3051\u3066\u3044\u307e\u305b\u3093\u304c\u9ad8\u9f62\u8005\u306a\u3069\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u6210\u4eba\u306b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u30592\uff09<\/sup>\uff0e\u307e\u305f\uff0c\u30ab\u30ca\u30c0\uff0c\u305d\u3057\u3066\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3092\u306f\u3058\u3081\u3068\u3059\u308bEU\u8af8\u56fd\u3067\u306f\u3046\u8755\u4e88\u9632\u7528\u9014\u3067\u8a8d\u53ef\u304c\u5f97\u3089\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\uff0e\u7c73\u56fd\u3084\u8c6a\u5dde\u306a\u3069\u6c34\u9053\u6c34\u6dfb\u52a0\u304c\u884c\u308f\u308c\u3066\u3044\u308b\u56fd\u3067\u306f\u30ab\u30ea\u30a8\u30b9\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u4eba\u3060\u3051\u306b\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u8a18\u4e8b\u3082\u898b\u304b\u3051\u307e\u3057\u305f\uff0e\u3053\u306e\u3042\u305f\u308a\u306f\u56fd\u306b\u3088\u3063\u3066\u3082\u4e8b\u60c5\u304c\u7570\u306a\u308b\u3088\u3046\u3067\u3059\uff0e\u65e5\u672c\u306b\u304a\u3051\u308b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u9069\u5fdc\u5916\u4f7f\u7528\u306b\u3064\u3044\u3066\u306f\u5f8c\u8ff0\u3057\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

(3)\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/p>\n

\u3000\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u3092\u6b6f\u9762\u306b\u5857\u5e03\u3057\u305f\u5834\u5408\uff0c\u30d5\u30c3\u5316\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u751f\u6210\u3055\u308c\uff0c\u6b6f\u78e8\u5264\u306a\u3069\u4f4e\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u3092\u6b6f\u9762\u306b\u5857\u5e03\u3057\u305f\u5834\u5408\u306f\u30d5\u30eb\u30aa\u30ed\u30a2\u30d1\u30bf\u30a4\u30c8\u304c\u751f\u6210\u3055\u308c\u308b\u3053\u3068\u306f\u3054\u5b58\u77e5\u3060\u3068\u601d\u3044\u307e\u3059\uff0e\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u306e5%NaF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3067\u51e6\u7406\u3059\u308b\u3053\u3068\u306b\u3088\u308a\uff0c\u8c61\u7259\u8cea\u30e2\u30c7\u30eb\u30d6\u30ed\u30c3\u30af\u306b\u9178\u62b5\u6297\u6027\u304c\u5f97\u3089\u308c\u308b3)4)<\/sup>\u3053\u3068\u304c\u57fa\u790e\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u300297%\u306e\u7121\u6a5f\u8cea(\u30cf\u30a4\u30c9\u30ed\u30ad\u30b7\u30a2\u30d1\u30bf\u30a4\u30c8)\u3092\u542b\u3080\u30a8\u30ca\u30e1\u30eb\u8cea\u3068\u6bd4\u8f03\u3057\u306670%\u3068\u7121\u6a5f\u8cea\u304c\u5c11\u306a\u3044\u8c61\u7259\u8cea\u3067\u3042\u3063\u3066\u3082\uff0c\u8c61\u7259\u8cea\u306e\u7121\u6a5f\u8cea\u3068\u53cd\u5fdc\u3057CaF2<\/sub>\u304c\u751f\u6210\u3055\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u306b\u3088\u308a\u751f\u6210\u3055\u308c\u305fCaF2<\/sub>\u306f\uff0c\u6b6f\u9762\u304b\u3089F\u30a4\u30aa\u30f3\u3092\u5f90\u653e\u3057\u6301\u7d9a\u7684\u306bF\u30a4\u30aa\u30f3\u3092\u4f9b\u7d66\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n

————————————————————————-<\/p>\n

\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3084\u6b6f\u9762\u5857\u5e03\u5264\u306a\u3069\u306e\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u306e\u5834\u5408<\/p>\n

\u3000Ca10<\/sub>(PO4<\/sub>)6<\/sub>(OH)2<\/sub>+2F–<\/sup>\u3000\u2192\u300010CaF2<\/sub>+6P4<\/sub>—<\/sup>+2OH–<\/sup><\/p>\n

\u30d5\u30c3\u5316\u7269\u6b6f\u78e8\u5264\u306a\u3069\u4f4e\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269\u306e\u5834\u5408<\/p>\n

\u3000Ca10(PO4<\/sub>)6<\/sub>(OH)2<\/sub>+2F–<\/sup>\u3000\u2192\u3000Ca10<\/sub>(PO4<\/sub>)6<\/sub>F2<\/sub>+2OH–<\/sup><\/p>\n

————————————————————————-<\/p>\n

\u3000\u305d\u308c\u3067\u306f\uff0c\u3069\u306e\u304f\u3089\u3044\u306e\u6df1\u3055\u307e\u3067\u52b9\u679c\u304c\u898b\u3089\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff0e5%NaF Duraphat\u3092\u5bfe\u8c61\u3068\u3057\u305finvitro\u8ad6\u6587\u3067\u306f1\u56de\u5857\u5e0312\u6642\u9593\u3067\u30a8\u30ca\u30e1\u30eb\u8cea\u8868\u5c6470\u03bcm \u307e\u3067\u8a8d\u3081\u3089\u308c\u305f\u3068\u5831\u544a5\uff09<\/sup>\u3055\u308c\u3066\u304a\u308a\uff0cF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u30821\u56de\u5857\u5e0312\u6642\u9593\u3067\u8c61\u7259\u8cea70\u03bcm\u307e\u3067\u8a8d\u3081\u3089\u308c\u305f\u3068\u5831\u544a6)<\/sup>\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u5b9f\u9a13\u6cd5\u3084\u88fd\u5264\u304c\u7570\u306a\u308b\u3053\u3068\uff0c\u30a8\u30ca\u30e1\u30eb\u8cea\u3068\u8c61\u7259\u8cea\u306e\u9055\u3044\u304c\u3042\u308b\u3053\u3068\u3092\u8003\u616e\u306b\u5165\u308c\u305f\u3068\u3057\u3066\u3082\uff0c\u8c61\u7259\u8cea\u3067\u3082\u5341\u5206\u30d5\u30c3\u5316\u7269\u304c\u53d6\u308a\u8fbc\u307e\u308c\u308b\u3067\u3042\u308d\u3046\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\uff0e\u3053\u306e\u3053\u3068\u304b\u3089\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u521d\u671f\u30a8\u30ca\u30e1\u30eb\u8cea\u3046\u8755\u306b\u52a0\u3048\uff0c\u521d\u671f\u6839\u9762\u3046\u8755\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e\u8d85\u9ad8\u9f62\u5316\u3092\u8fce\u3048\uff0c\u6839\u9762\u3046\u8755\u306b\u5bfe\u3057\u3066\u5bfe\u5fdc\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u308b\u308f\u304c\u56fd\u306b\u304a\u3044\u3066\u3082\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u6d3b\u7528\u306f\u6709\u7528\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e<\/p>\n

(4)\u4ed6\u5264\u5f62\u3068\u306e\u6bd4\u8f03<\/strong><\/p>\n

\u3000\u65e5\u672c\u306e\u6b6f\u79d1\u533b\u9662\u3067\u5857\u5e03\u3055\u308c\u308b\u5834\u5408\uff0c9,000ppm\u306e\u30d5\u30c3\u5316\u7269\u30b2\u30eb\u3092\u7dbf\u7403\u3067\u5857\u5e03\u3059\u308b\u7dbf\u7403\u5857\u5e03\u6cd5\u304c\u4e00\u822c\u7684\u306a\u3088\u3046\u3067\u3059\uff0e\u6b6f\u79d1\u5148\u9032\u56fd\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3067\u306f\uff0c\u73fe\u5728\u306f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u5857\u5e03\u3059\u308b\u3053\u3068\u304c\u591a\u3044\u3088\u3046\u3067\u3059\uff0e<\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u7dbf\u7403\u5857\u5e03\u6cd5\u306a\u3069\u3067\u7528\u3044\u3089\u308c\u308b9,000ppm\u3068\u6bd4\u8f03\u3057\u306622,600ppm\u3068\u7d042.5\u500d\u307b\u3069\u9ad8\u6fc3\u5ea6\u3067\u3042\u308a\uff0c\u6b6f\u9762\u3067\u786c\u5316\u3057\u30d5\u30c3\u7d20\u30a4\u30aa\u30f3\u3092\u6301\u7d9a\u7684\u306b\u5f90\u653e\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u51e6\u7f6e(\u5857\u5e03)\u9593\u9694\u3092\u4f38\u3070\u3059\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\uff0e\u5831\u544a\u3067\u306f\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u57fa\u672c\uff16\u304b\u6708\u306b\uff11\u56de\u5857\u5e03\uff0c\u30ab\u30ea\u30a8\u30b9\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u306a\u3069\u306f\uff13\u304b\u6708\u306b\uff11\u56de\u5857\u5e03\u3059\u308b7)<\/sup>\u3053\u3068\u304c\u591a\u3044\u3088\u3046\u3067\u3059\uff0e\u4e00\u65b9\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u5f8c\u306b\u98f2\u98df\u3092\u63a7\u3048\u308b\u6642\u9593\u304c\u5fc5\u8981\u3060\u3063\u305f\u308a\uff0c\u30b3\u30b9\u30c8\u306e\u9762\u3067\u306f\u7dbf\u7403\u5857\u5e03\u6cd5\u306b\u5206\u304c\u3042\u308b\u3088\u3046\u306b\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u914d\u5408\u6b6f\u78e8\u5264\u3084\u30d5\u30c3\u5316\u7269\u6d17\u53e3\u5264\u306f\u4f4e\u6fc3\u5ea6\u3067\u3042\u308a\uff0c\u7279\u306b\u30d5\u30c3\u5316\u7269\u914d\u5408\u6b6f\u78e8\u5264\u3067\u306f\u553e\u6db2\u306b\u3088\u3063\u3066\u901f\u3084\u304b\u306b\u52b9\u679c\u304c\u6e1b\u5f31\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff0e\u4e00\u65b9\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u6b6f\u9762\u306b\u4ed8\u7740\u3057\u786c\u5316\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u9577\u6642\u9593\u30d5\u30c3\u5316\u7269\u3092\u5f90\u653e\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\uff0e\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F\u306f\uff14\u6642\u9593\uff0c\u6b6f\u9762\u306b\u4ed8\u7740\u3059\u308b\u3088\u3046\u306b\u3059\u308c\u3070\uff0c24\u6642\u9593\u30d5\u30c3\u7d20\u306b\u52a0\u3048\u30ea\u30f3\u30fb\u30ab\u30eb\u30b7\u30a6\u30e0\u3092\u5f90\u653e\u3059\u308b4)<\/sup>\u3068\u3057\u3066\u3044\u307e\u3059\uff0e\u3053\u308c\u306f\u3069\u3061\u3089\u304c\u826f\u3044\u3068\u304b\u305d\u3046\u3044\u3046\u8a71\u3067\u306f\u306a\u304f\uff0c\u5264\u5f62\u306b\u3088\u308b\u7279\u6027\u306e\u9055\u3044\u3067\u3059\uff0e\u60a3\u8005\u3055\u3093\u306e\u30ea\u30b9\u30af\u306b\u5fdc\u3058\u3066\uff0c\u57fa\u672c\u7684\u306b\u306f\u7d44\u307f\u5408\u308f\u305b\u3066\u7528\u3044\u308b\u3053\u3068\u304c\u809d\u8981\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e<\/p>\n

 <\/p>\n

\uff12\uff0e\u9069\u5fdc\u5916\u4f7f\u7528\u306b\u3064\u3044\u3066<\/h2>\n

\u3000\u73fe\u5728\uff0c\u65e5\u672c\u3067\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u300cF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u300d\u300c\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F\u300d\u300c\u30a8\u30ca\u30e1\u30e9\u30b9\u30c8\u300d\u306f\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u306e\u9069\u5fdc\u3057\u304b\u6709\u3057\u3066\u304a\u3089\u305a\uff0c\u3046\u8755\u4e88\u9632(\u6291\u5236)\u5264\u3068\u3057\u3066\u9069\u5fdc\u3092\u6709\u3057\u3066\u3044\u307e\u305b\u3093\uff0e\u3053\u308c\u306f\u8abf\u3079\u305f\u9650\u308a\u3060\u3068\u7c73\u56fd\uff0c\u82f1\u56fd\uff0c\u8c6a\u5dde\u3067\u3082\uff0c\u3046\u8755\u4e88\u9632(\u6291\u5236)\u5264\u3068\u3057\u3066\u306e\u8a8d\u53ef\u306f\u53d7\u3051\u3066\u3044\u307e\u305b\u3093\uff0e\u3053\u306e\u3042\u305f\u308a\u306e\u8a8d\u8b58\u30fb\u4e8b\u60c5\u30fb\u308f\u304c\u56fd\u3067\u306e\u5bfe\u5fdc\u306b\u3064\u3044\u3066\u5c11\u3057\u89e6\u308c\u3066\u304a\u304d\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u307e\u305a\uff0c\u3053\u308c\u3089\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\uff0c\u3082\u3068\u3082\u3068\u785d\u9178\u9280\u306b\u5909\u308f\u308b\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u958b\u767a\u30fb\u81e8\u5e8a\u5fdc\u7528\u3055\u308c\u305f\u7d4c\u7def8)9<\/sup>)<\/sup>\u304c\u3042\u308a\uff0c\u65e5\u672c\u3067\u30821970\u5e74\u4ee3\u306b\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u8a66\u4f5c\u3055\u308c\u3066\u3044\u307e\u3057\u305f3)<\/sup>\uff0e\u4e16\u754c\u7684\u306b\u307f\u3066\u3082\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u958b\u767a\u3055\u308c\uff0c\u3046\u8755\u4e88\u9632(\u6291\u5236)\u5264\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305f\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u306a\u3044\u3088\u3046\u3067\u3059\uff0e<\/p>\n

\u3000\u9069\u5fdc\u5916\u306b\u4f7f\u7528\u3057\u305f\u5834\u5408\u306f\u539f\u5247\u3068\u3057\u3066\u81ea\u8cbb\u8a3a\u7642\u6271\u3044\u3068\u306a\u308a\uff0c\u4fdd\u967a\u8acb\u6c42\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\uff0e\u3064\u307e\u308a\uff0c\u4fdd\u967a\u8a3a\u7642\u306b\u304a\u3044\u3066\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u4f7f\u7528\u3057\u3066\u30d5\u30c3\u5316\u7269\u5c40\u6240\u5fdc\u7528(F\u5c40)\u3092\u7b97\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\uff0e\u3057\u304b\u3057\u300c\u4fdd\u967a\u8a3a\u7642\u306b\u304a\u3051\u308b\u533b\u85ac\u54c1\u306e\u53d6\u6271\u3044\u306b\u3064\u3044\u3066(\u662d\u548c55 \u5e74\uff19\u6708\uff13\u65e5\u4ed8\u4fdd\u767a\u7b2c 51\u53f7\u539a\u751f\u7701\u4fdd\u967a\u5c40\u9577\u901a\u77e5)\u300d\u306b\u300c\u85ac\u7406\u4f5c\u7528\u306b\u57fa\u3065\u304d\u51e6\u65b9\u3055\u308c\u305f\u5834\u5408\u306b\u306f\u3001\u8a3a\u7642\u5831\u916c\u660e\u7d30\u66f8\u306e\u533b\u85ac\u54c1\u306e\u5be9\u67fb\u306b\u5f53\u305f\u308a\uff0c\u5b66\u8853\u7684\u306b\u6b63\u3057\u304f\uff0c\u307e\u305f\uff0c\u5168\u56fd\u7d71\u4e00\u7684\u306a\u5bfe\u5fdc\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u308b\u300d\u3068\u8a18\u8f0910\uff09<\/sup>\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u3064\u307e\u308a\u9069\u5fdc\u5916\u4f7f\u7528\u3067\u3042\u3063\u3066\u3082\u5b66\u4f1a\u306a\u3069\u304c\u6b63\u3057\u304f\u5be9\u67fb\u3092\u8acb\u6c42\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u85ac\u4e8b\u627f\u8a8d\u30fb\u4fdd\u967a\u9069\u5fdc\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff0e\u533b\u79d1\u3067\u306f\u3053\u306e\u3088\u3046\u306a\u8a3a\u67fb\u4e8b\u4f8b\u304c\u6bd4\u8f03\u7684\u3088\u304f\u3042\u308a\u307e\u3059\uff0e<\/p>\n

\u3000\u73fe\u72b6\uff0c\u30e1\u30fc\u30ab\u30fc\u306f\u6b6f\u79d1\u533b\u5e2b\u306a\u3069\u3078\u60c5\u5831\u63d0\u4f9b\u3059\u308b\u969b\u306b\u300c\u3046\u8755\u4e88\u9632\u76ee\u7684\u306b\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u300d\u3068\u8b33\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\uff0e\u3046\u8755\u4e88\u9632\u76ee\u7684\u306b\u4f7f\u3046\u3053\u3068\u306f\u6b6f\u79d1\u533b\u5e2b\u306e\u5224\u65ad\u30fb\u88c1\u91cf\u3067\u3042\u3063\u3066\uff0c\u7f70\u5247\u7b49\u306f\u306a\u3044\u3088\u3046\u3067\u3059\uff0e\u305f\u3060\uff0c\u5927\u5b66\u75c5\u9662\u7b49\u3067\u306f\u7533\u8acb\u304c\u5fc5\u8981\u3060\u3063\u305f\u308a\u3057\u307e\u3059\uff0e\u958b\u696d\u533b\u3067\u3042\u3063\u3066\u3082\u9069\u5fdc\u5916\u4f7f\u7528\u3068\u306a\u308b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u3046\u8755\u4e88\u9632\u76ee\u7684\u306b\u4f7f\u7528\u3059\u308b\u969b\u306f\uff0c\u60a3\u8005\u3055\u3093\u306b\u9069\u5207\u306b\u8aac\u660e\u3092\u884c\u3044\u540c\u610f\u3092\u5f97\u3066\u304a\u304f\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u3046\u8755\u4e88\u9632\u306b\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u3053\u3068\u306f\u591a\u304f\u306e\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304a\u308a\uff0c\u30d5\u30c3\u5316\u7269\u304c\u3046\u8755\u4e88\u9632\u306b\u6709\u52b9\u306a\u3053\u3068\u306f\u7d1b\u308c\u3082\u306a\u3044\u4e8b\u5b9f\u3067\u3059\u306e\u3067\uff0c\u6b6f\u79d1\u533b\u5e2b\u306e\u88c1\u91cf\u3067\u4f7f\u7528\u3057\u3066\u69cb\u3044\u307e\u305b\u3093\uff0e\u305f\u3060\uff0c\u60a3\u8005\u3055\u3093\u306b\u8aac\u660e\u3057\u3066\u540c\u610f\u3092\u5f97\u3066\u304a\u304f\u3053\u3068\u306f\u5fc5\u8981\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e<\/p>\n

 <\/p>\n

\uff13\uff0e\u4f7f\u7528\u65b9\u6cd5\u3068\u5b89\u5168\u6027\uff08\u5e7c\u5150\u30fb\u5c0f\u5150\u3078\u306e\u9069\u5fdc\uff09<\/h2>\n

(1)\u4f7f\u7528\u91cf<\/strong><\/p>\n

\u3000\u4e88\u9632\u6b6f\u79d1\u7528\u9014\u3067\u4f7f\u7528\u3059\u308b\u5834\u5408\uff0cDuraphat\u00ae<\/sup>\u3067\u306f\u4ee5\u4e0b\u306e\u7528\u91cf\u3067\u4f7f\u7528\u3059\u308b\u3053\u3068\u3068\u660e\u8a18\u3055\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n\n\n\n\n\n
\n

\u4e73\u6b6f\u5217<\/p>\n<\/td>\n

\n

\uff5e0.25ml(5.65mgF)<\/p>\n<\/td>\n<\/tr>\n

\n

\u6df7\u5408\u6b6f\u5217<\/p>\n<\/td>\n

\n

\uff5e0.40ml(9.04mgF)<\/p>\n<\/td>\n<\/tr>\n

\n

\u6c38\u4e45\u6b6f\u5217<\/p>\n<\/td>\n

\n

\uff5e0.75ml(16.95mgF)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u3000\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u5f8c\u8ff0\u3057\u307e\u3059\u304c\uff0c\u9069\u6b63\u306a\u4f7f\u7528\u65b9\u6cd5\u3084\uff0c\u5e74\u9f62\u306b\u5fdc\u3058\u305f\u9069\u6b63\u91cf\u306e\u4f7f\u7528\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u30597)11)<\/sup>\uff0e\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F\u306e\u5834\u5408\uff0c\uff11\u5305\u304c0.5ml\u3067\u3059\u306e\u3067\uff0c\u4e73\u6b6f\u3084\u6df7\u5408\u6b6f\u5217\u306b\u5168\u91cf\u4f7f\u7528\u3059\u308b\u3053\u3068\u306f\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u3044\u3082\u306e\u306e\u904e\u91cf\u4f7f\u7528\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e\u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F\u306b\u306f\u4f7f\u7528\u91cf\u306e\u30ac\u30a4\u30c9\u3068\u306a\u308b\u30a4\u30e9\u30b9\u30c8\u3068\u300c\uff11\u56de\u5206\u306e\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u5168\u3066(\u30a4\u30e9\u30b9\u30c8\u306e)\u5186\u306e\u4e2d\u306b\u51fa\u3057\u3066\uff0c\u5185\u5074\u306e\u5186\u3067\u3088\u304f\u6df7\u305c\u307e\u3059\uff0e\u5bb9\u91cf\u306e\u7d75\u3092\u53c2\u8003\u306b\u9069\u91cf\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u300d\u3068\u306e\u8aac\u660e\u6587(\u82f1\u6587)\u304c\u5916\u88c5\u888b\u306b\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\"\"<\/p>\n

fig.2 \u30af\u30ea\u30f3\u30d7\u30ed\u30db\u30ef\u30a4\u30c8\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5F\u306e\u5916\u88c5\u888b<\/p>\n

\u3000\u4e73\u6b6f\u5217\u306b\u4f7f\u7528\u3059\u308b\u969b\u306f\uff0c\uff11\u5305\u306e\u534a\u5206\u7a0b\u5ea6\u3092\u76ee\u5b89\u306b\u3057\u3066\u6709\u5bb3\u4e8b\u8c61\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\uff0e\u305f\u3060\uff0c\u65e5\u672c\u3067\u306e\u8ca9\u58f2\u306f\u3042\u304f\u307e\u3067\u77e5\u899a\u904e\u654f\u6291\u5236\u5264\u3068\u3057\u3066\u8a8d\u53ef\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3067\u3042\u308b\u305f\u3081\uff0c\u4e73\u5150\u306b\u5bfe\u3059\u308b\u7d30\u304b\u3044\u30c7\u30fc\u30bf\u306f\u306a\u3044\u3088\u3046\u3067\u3059\uff0e\u60a3\u8005\u3055\u3093\u306b\u5fdc\u3058\u305f\u9069\u91cf\u4f7f\u7528\u3092\u5fc3\u304c\u3051\u305f\u3044\u3067\u3059\u306d\uff0e<\/p>\n

(2)\u30a2\u30ec\u30eb\u30ae\u30fc<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u306f\u308f\u305a\u304b2\uff09<\/sup>\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\uff0c\u30ed\u30b8\u30f3\u30a2\u30ec\u30eb\u30ae\u30fc\uff0c\u6f70\u760d\u6027\u6b6f\u8089\u708e\uff0c\u53e3\u5185\u708e\uff0c\u6c17\u7ba1\u652f\u5598\u606f\u306a\u3069\u3092\u6709\u3059\u308b\u5834\u5408\u306f\u5857\u5e03\u3092\u63a7\u3048\u308b\u3088\u3046\u6dfb\u4ed8\u6587\u7ae0\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u30597)<\/sup>\uff0e\u307e\u305f\uff0c\u6eb6\u5a92\u3068\u3057\u3066\u30a8\u30bf\u30ce\u30fc\u30eb\u304c\u542b\u307e\u308c\u3066\u3044\u308b(\u30d5\u30c3\u5316\u7269\u3067\u306f\u306a\u304f\u30ed\u30b8\u30f3\u306e\u6eb6\u5a92)\u305f\u3081\uff0c\u30a2\u30eb\u30b3\u30fc\u30eb\u306b\u654f\u611f\u306a\u5834\u5408\u306f\u907f\u3051\u305f\u307b\u3046\u304c\u3088\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n

(3)\u5b89\u5168\u6027\u306b\u3064\u3044\u3066<\/strong><\/p>\n

\u3000\u4e00\u822c\u7684\u306b\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u7dbf\u7403\u5857\u5e03\u6cd5\u3067\u4f7f\u7528\u3055\u308c\u308b9,000ppm\u306e\u30d5\u30c3\u5316\u7269\u88fd\u5264\u3088\u308a\u3082\u5b89\u5168\u6027\u304c\u9ad8\u3044\u3068\u8a00\u308f\u308c\u307e\u3059\uff0e\u306a\u305c\u5b89\u5168\u3068\u8a00\u3048\u308b\u306e\u304b\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u5f8c\u306e\u85ac\u7269\u52d5\u614b\u306b\u95a2\u3059\u308b\u7814\u7a76\u3068\uff0c\u6025\u6027\u4e2d\u6bd2\u91cf\u306e\u8a08\u7b97\u3092\u5143\u306b\u8003\u5bdf\u3057\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\u2460\u85ac\u7269\u52d5\u614b<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\uff0c\u9ad8\u6fc3\u5ea6\u30d5\u30c3\u5316\u7269(22,600ppm)\u3092\u914d\u5408\u3057\u3066\u3044\u308b\u306b\u3082\u95a2\u308f\u3089\u305a\u5e7c\u5150\u30fb\u5c0f\u5150\u3068\u3082\u306b\u85ac\u7269\u52d5\u614b\u4e0a\uff0c\u5b89\u5168\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u30591\uff0912\uff09<\/sup>\uff0e \u5b89\u5168\u3060\u3068\u3059\u308b\u7406\u7531\u306f\uff0c\u305d\u3082\u305d\u3082\uff11\u56de\u306e\u4f7f\u7528\u91cf\u304c\u6700\u59270.5ml\u3068\u5c11\u306a\u3044\u3053\u3068\u306b\u52a0\u3048\uff0c\u30ed\u30b8\u30f3\u306b\u3088\u3063\u3066\u786c\u5316\u3057\u6d88\u5316\u7ba1\u3067\u307b\u3068\u3093\u3069\u5438\u53ce\u3055\u308c\u306a\u3044\u304b\u3089\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u305913)<\/sup>\uff0e\u4e73\u5150(\u751f\u5f8c12\u304b\u6708\uff5e15\u304b\u6708)\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u3082\u5c3f\u4e2d\u306e\u30d5\u30c3\u5316\u7269\u91cf\u304b\u3089\u63a8\u5b9a\u3057\u305f\u8840\u6f3f\u4e2d\u85ac\u7269\u6fc3\u5ea6\u306f\u57fa\u6e96\u3092\u8d85\u3048\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u305914)<\/sup>\uff0e\u307e\u305f\uff0c\u540c\u69d8\u306e\u8a66\u9a13\u30673\uff5e\uff14\u6b73\u5150\u3067\u306e\u5b89\u5168\u6027\u3082\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u305915)<\/sup>\uff0cFDA\u306e\u5831\u544a\u306b\u3088\u308b\u30682010\u5e74\u304b\u30892020\u5e74\u306e10\u5e74\u9593\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u6709\u5bb3\u4e8b\u8c61\u306f65\u4ef6\uff0c\u3044\u305a\u308c\u3082\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u5272\u306b\u6709\u5bb3\u4e8b\u8c61\u304c\u5c11\u306a\u304f\uff0c\u6b7b\u4ea1\u4f8b\u3082\u5831\u544a\u304c\u306a\u304f\u5b89\u5168\u306b\u4f7f\u7528\u3067\u304d\u308b\u88fd\u54c1\u3067\u3042\u308b\u3068\u5831\u544a16)<\/sup>\u3055\u308c\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\u2461\u6025\u6027\u4e2d\u6bd2<\/strong><\/p>\n

\u3000\u4f55\u3089\u304b\u306e\u533b\u7642\u51e6\u7f6e\u304c\u5fc5\u8981\u3068\u3055\u308c\u308b\u30d5\u30c3\u7d20\u6025\u6027\u4e2d\u6bd2\u91cf(5mg\/5kg)\u3092\u4e0b\u306e\u8868\u306b\u793a\u3057\u307e\u3059(\u4fbf\u5b9c\u4e0a1ml\u30921g\u3068\u3057\u3066\u3044\u307e\u3059\uff0e(\u8a08\u7b97\u9593\u9055\u3044\u304c\u3042\u308a\u307e\u3057\u305f\u3089\u3054\u6307\u6458\u304f\u3060\u3055\u3044))\uff0e5%\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5264\u306f22,600ppm\u3068\u9ad8\u6fc3\u5ea6\u3067\u3042\u308b\u3082\u306e\u306e\uff0c\u4f7f\u7528\u91cf\u304c1\u5305(1\u56de\u5206)\u30670.5ml(\u4e73\u6b6f\u5217\u306e\u5834\u5408\u306f0.25ml)\u3068\u5c11\u306a\u304f\uff0c2%NaF\u306e\u5857\u5e03\u7528\u30b8\u30a7\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u305d\u308c\u307b\u3069\u5909\u308f\u3089\u306a\u3044\u7d50\u679c\u306b\u306a\u3063\u3066\u3044\u307e\u3059\uff0e\u307e\u305f\uff0c\u904e\u91cf\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u304c\u554f\u984c\u306b\u306a\u308a\u307e\u3059\u304c\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u6b6f\u79d1\u533b\u5e2b\u30fb\u6b6f\u79d1\u885b\u751f\u58eb(\u56fd\u306b\u3088\u3063\u3066\u306f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u53d7\u3051\u305f\u30c7\u30f3\u30bf\u30eb\u30ca\u30fc\u30b9)\u306b\u3088\u308a\u5857\u5e03\u3055\u308c\uff0c\u3055\u3089\u306b\u65b0\u3057\u3044\u4e16\u4ee3\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f1\u56de0.5ml\u304c\uff11\u5305\u306b\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3067\u8aa4\u98f2\u306a\u3069\u73fe\u5b9f\u7684\u306b\u4e2d\u6bd2\u306b\u306a\u308b\u3088\u3046\u306a\u904e\u91cf\u6442\u53d6\u306f\u8d77\u3053\u3089\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e<\/p>\n

\"\"Table.1\u300015kg(4\u6b73\u5150)\u306e\u5834\u5408\u306e\u6025\u6027\u4e2d\u6bd2\u91cf(Whitford 5mg\/kg)<\/p>\n

 <\/p>\n

\n\uff14\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u3046\u8755\u6291\u5236\u52b9\u679c<\/h2>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u3046\u8755\u6291\u5236\u52b9\u679c\u306f\u3069\u306e\u304f\u3089\u3044\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306b\u306f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u304c\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\uff0e22\u8a66\u9a13\uff0c12,455\u4eba(9,595\u4eba)\u3092\u5bfe\u8c61\u3068\u3057\u305f2013\u5e74\u306e\u30b3\u30af\u30e9\u30f3\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u6c38\u4e45\u6b6f\u306b\u5bfe\u3059\u308b13 \u8a66\u9a13\u306b\u3064\u3044\u3066\u306eDMFS \u4e88\u9632\u7387\u306f 43%\uff0c \u4e73\u6b6f\u306b\u5bfe\u3059\u308b10\u8a66\u9a13\u306b\u3064\u3044\u3066\u306edmfs\u4e88\u9632\u7387\u306f37\uff05\u3068\u5831\u544a17)<\/sup>\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u307e\u305f\uff0c\u6bd4\u8f03\u7684\u65b0\u3057\u3044(2020\u5e74)\u82f1\u56fd\u30b7\u30a7\u30d5\u30a3\u30fc\u30eb\u30c9\u5927\u5b66\u306e16\u306e\u7814\u7a76\u3092\u57fa\u306b\u3057\u305f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u308231.13%\u306e\u3046\u8755\u6291\u5236\u52b9\u679c\u3092\u6709\u3057\u3066\u3044\u308b\u3068\u7d50\u8ad6\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u305918\uff09<\/sup>\uff0e<\/p>\n

\u3000\u4e0b\u306e\u8868\u3067\u3046\u8755\u6291\u5236\u52b9\u679c\u306b\u3064\u3044\u3066\u4ed6\u5264\u5f62\u3068\u6bd4\u8f03\u3057\u3066\u307f\u307e\u3057\u305f\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u3046\u8755\u6291\u5236\u52b9\u679c\u306f2013\u5e74\u306e\u30b3\u30af\u30e9\u30f3\u30ec\u30d3\u30e5\u30fc17)<\/sup>\uff0c\u305d\u306e\u4ed6\u306f\u624b\u5143\u306b\u3042\u3063\u305f\u65b0\u4e88\u9632\u6b6f\u79d1\u5b66\u7b2c\uff14\u7248\u533b\u6b6f\u85ac\u51fa\u724819)<\/sup>\u3092\u53c2\u7167\u3057\u3066\u8868\u306b\u3057\u3066\u3042\u308a\u307e\u3059\uff0e\u3053\u306e\u3046\u8755\u6291\u5236\u7387\u3068\u3044\u3046\u306e\u306f\u975e\u5e38\u306b\u3056\u3063\u304f\u308a\u3068\u7b97\u51fa\u3055\u308c\u3066\u304a\u308a\u307e\u3057\u3066\uff0c\u3042\u307e\u308a\u53c2\u8003\u306b\u306a\u308a\u307e\u305b\u3093\u304c\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u4ed6\u306e\u30d5\u30c3\u5316\u7269\u88fd\u5264\u3068\u6bd4\u8f03\u3057\u3066\u3082\u905c\u8272\u306e\u306a\u3044\u6570\u5024\u304c\u51fa\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308b\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\"\"<\/p>\n

Table.2 \u5404\u5264\u5f62\uff0c\u5fdc\u7528\u6cd5\u306b\u3088\u308b\u3046\u8755\u6291\u5236\u7387<\/p>\n

\n\uff15\uff0e\u8cbb\u7528\u5bfe\u52b9\u679cCost & Benefit\u3078\u306e\u7591\u554f<\/h2>\n

\u3000\u6587\u732e\u306b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u52b9\u679c\u304c\u306a\u304b\u3063\u305f\u3068\u3059\u308b\u3082\u306e\u3084\uff0c\u8cbb\u7528\u5bfe\u52b9\u679c\u304c\u3088\u304f\u306a\u3044\u3068\u3059\u308b\u6587\u732e\u304c\u307f\u3089\u308c\u307e\u3057\u305f\uff0e\u3053\u306e\u3042\u305f\u308a\u306e\u4e8b\u60c5\u306b\u3064\u3044\u3066\u8ad6\u6587\u3092\u3054\u7d39\u4ecb\u3057\u3066\uff0c\u5c11\u3057\u8003\u5bdf\u3057\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\u30001\uff5e\uff14\u6b73\u3092\u5bfe\u8c61\u3068\u3057\u3066\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u5e74\uff12\u56de\u00d7\uff12\u5e74\u9593\u5857\u5e03\u3057\u3066\u3082\uff0c\u3046\u8755\u306e\u767a\u751f\u7387\u306f\u6e1b\u5c11\u3057\u306a\u304b\u3063\u305f20)<\/sup>\u3068\u3059\u308b\u8ad6\u6587\uff0c2\uff5e5\u6b73\u3092\u5bfe\u8c61\u3068\u3057\u3066\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5(7,000ppm)\u3092\u6b6f\u78e8\u5264(1,000ppm)\u5229\u7528\u74b0\u5883\u4e0b\u30672\u5e74\u9593\u5857\u5e03\u3057\u3066\u3082\u6709\u610f\u306a\u3046\u8755\u4e88\u9632\u52b9\u679c\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u3068\u3059\u308b\u8ad6\u658721)<\/sup>\uff0e\u30d5\u30c3\u5316\u7269\u914d\u5408\u6b6f\u78e8\u5264\uff081,000 ppm\u4ee5\u4e0a\uff09\u306b\u3088\u308b\u6bce\u65e5\u306e\u6b6f\u78e8\u304d\u306e\u88dc\u52a9\u3068\u3057\u3066\u5857\u5e03\u3055\u308c\u305f\u5834\u5408\uff0c\u5c0f\u5150\uff088\u6b73\u672a\u6e80\uff09\u306b\u5bfe\u3059\u308b\u3046\u8755\u4e88\u9632\u306e\u6709\u610f\u306a\u6709\u76ca\u6027\u306f\u306a\u3044\u3068\u3059\u308b\u8ad6\u658722)<\/sup>\uff0e1\uff5e3\u6b73\u306e\u5c0f\u5150\u306b\u5bfe\u3057\u5e74\uff12\u56de\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u304c\uff0c\u3046\u8755\u4e88\u9632\u3084\u3046\u8755\u306e\u9032\u884c\u6291\u5236\u306b\u5bc4\u4e0e\u3057\u306a\u304b\u3063\u305f\u3068\u3059\u308b\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u306e\u8ad6\u658723)<\/sup>\u304c\u898b\u3089\u308c\u307e\u3057\u305f\uff0e\u3055\u3089\u306b\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u7d71\u8a08\u5b66\u7684\u306b\u6709\u52b9\u3068\u306f\u8a00\u3048\u305a\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u5206\u6790\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u3057\u305f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc24\uff09<\/sup>\u3082\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u307e\u305f\uff0c\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u30fb\u30b9\u30c8\u30c3\u30af\u30db\u30eb\u30e0\u3067\u884c\u308f\u308c\u305f3,403 \u4eba\u306e\u5b50\u3069\u3082\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5e74 2 \u56de\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u3092\u8ffd\u52a0\u3057\u305f\u3046\u8755\u4e88\u9632\u30d7\u30ed\u30b0\u30e9\u30e0\u300cStop Caries Stockholm\u300d\uff08SCS\uff09\u3067\u306f\uff0c\u53e3\u8154\u5185\u7d30\u83cc\u53e2\u306b\u306f\u307b\u3068\u3093\u3069\u5f71\u97ff\u3092\u4e0e\u3048\u305a\uff0c\u3046\u8755\u306e\u767a\u751f\u3092\u6709\u610f\u306b\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u306f\u306a\u304b\u3063\u305f\uff0e\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u512a\u308c\u3066\u3044\u308b\u3068\u8a00\u3048\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305925\uff09<\/sup>\uff0e\u65e5\u672c\u306b\u8fd1\u3044\u53f0\u6e7e\u306e\u7814\u7a76\u3067\u3082\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u96c6\u56e3\u5857\u5e03\u306b\u61d0\u7591\u7684\u306a\u610f\u898b\u304c\u898b\u3089\u308c\u3066\u3044\u307e\u305926\uff09<\/sup>\uff0e<\/p>\n

\u3000\u516c\u8846\u885b\u751f\u7684\u306b\u306f\u6b6f\u78e8\u5264\u3084\u30d5\u30ed\u30ea\u30c7\u30fc\u30b7\u30e7\u30f3\u306e\u307b\u3046\u304c\u8cbb\u7528\u5bfe\u52b9\u679c\u304c\u826f\u597d\u3067\u3042\u308b\u3068\u3044\u3046\u7d50\u679c\u306b\u306a\u308b\u306e\u3060\u3068\u601d\u308f\u308c\u307e\u3059\uff0e\u3053\u306e\u3088\u3046\u306a\u8907\u6570\u306e\u7814\u7a76\u30c7\u30fc\u30bf\u304b\u3089\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\uff0c\u3088\u308a\u591a\u304f\u306e\u4eba\u3092\u5bfe\u8c61\u3068\u3059\u308b\u30dd\u30d4\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u30a2\u30d7\u30ed\u30fc\u30c1\u3078\u306e\u5229\u7528\u3088\u308a\u3082\uff0c\u3088\u308a\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u4eba\uff0c\u3046\u8755\u304c\u5b58\u5728\u3059\u308b\u4eba\u3092\u5bfe\u8c61\u3068\u3059\u308b\u30cf\u30a4\u30ea\u30b9\u30af\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308b\u307b\u3046\u304c\u6709\u52b9\u3067\u30b3\u30b9\u30c8\uff06\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u304c\u826f\u597d\u306b\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u8003\u3048\u307e\u3057\u305f\uff0e<\/p>\n

\u3000\u3053\u306e\u8cbb\u7528\u5bfe\u52b9\u679c\u306b\u3064\u3044\u3066\uff0c\u65e5\u672c\u3067\u306f\u7121\u8996\u3055\u308c\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u591a\u3044\u306e\u3067\u3059\u304c\u30fb\u30fb\u30fb\u4e88\u9632\u6b6f\u79d1\u3092\u8003\u3048\u308b\u6642\uff0c\u5148\u9032\u56fd\u306e\u30af\u30ea\u30cb\u30c3\u30af\u306b\u6765\u9662\u3055\u308c\u308b\u60a3\u8005\u3055\u3093\u306e\u3046\u8755\u4e88\u9632\u3060\u3051\u3067\u306f\u306a\u304f\uff0c\u4e16\u754c\u306e\u3069\u3053\u304b\u306e\u8ca7\u3057\u3044\u4eba\u307e\u3067\u8001\u82e5\u7537\u5973\u554f\u308f\u305a\u3046\u8755\u304b\u3089\u6551\u3046\u3053\u3068\u304c\u51fa\u6765\u308b\u304b\u306f\u975e\u5e38\u306b\u5927\u5207\u306a\u3053\u3068\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e<\/p>\n

 <\/p>\n

\uff16\uff0e\u307e\u3068\u3081\u30fb\u81e8\u5e8a\u5fdc\u7528\u306e\u30b3\u30c4<\/h2>\n

\u00a0 \u52e4\u52d9\u5148\u3067\u306f\u30d5\u30c3\u5316\u7269\u6b6f\u78e8\u5264\uff0c\u30d5\u30c3\u5316\u7269\u6d17\u53e3\u5264\u306b\u52a0\u3048\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u6709\u52b9\u306b\u6d3b\u7528\u3057\u3066\u3044\u307e\u3059\uff0e\u3042\u3093\u307e\u308a\u4f7f\u3063\u305f\u3053\u3068\u304c\u306a\u3044\u305e\u3068\u3044\u3046\u6b6f\u79d1\u533b\u3084\u6b6f\u79d1\u885b\u751f\u58eb\u3055\u3093\u5411\u3051\u306b\u81e8\u5e8a\u5fdc\u7528\u306e\u30b3\u30c4\u3092\u66f8\u3044\u3066\u307f\u3088\u3046\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

(1)\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u308b\u75c7\u4f8b<\/strong><\/p>\n

\u3000\u524d\u8ff0\u306e\u3068\u304a\u308a\u8cbb\u7528\u5bfe\u52b9\u679c\u3092\u8003\u616e\u3059\u308b\u3068\uff0c\u30dd\u30d4\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u306f\u4e0d\u5411\u304d\u306e\u3088\u3046\u306a\u6c17\u304c\u3057\u307e\u3059\uff0e\u305f\u3060\uff0c\u7121\u52b9\u3068\u3044\u3046\u3088\u308a\u306f\uff0c\u6b6f\u78e8\u5264\u3084\u6d17\u53e3\u5264\uff0c\u30d5\u30ed\u30ea\u30c7\u30fc\u30b7\u30e7\u30f3\u7b49\u306e\u512a\u5148\u9806\u4f4d\u304c\u9ad8\u3044\u3068\u3044\u3046\u3053\u3068\u3092\u610f\u5473\u3057\u3066\u3044\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u7c73\u56fd\u6b6f\u79d1\u533b\u5e2b\u4f1a(ADA)\u3067\u306f\uff0c6\u6b73\u672a\u6e80\u306e\u5c0f\u5150\u306b\u306f2.26\u30d1\u30fc\u30bb\u30f3\u30c8\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u63a8\u5968\u3055\u308c\uff0c6\u6b73\u4ee5\u4e0a\u306e\u60a3\u8005\u306b\u306f\u30012.26\uff05\u306e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u30011.23\uff05\u306eAPF\u30b2\u30eb\u3001\u307e\u305f\u306f\u5bb6\u5ead\u75280.05\uff05\u306e\u30d5\u30c3\u5316\u7269\u30b2\u30eb\u307e\u305f\u306f\u30da\u30fc\u30b9\u30c8\u30010.09\uff05\u306e\u30d5\u30c3\u5316\u7269\u6d17\u53e3\u5264\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u305927)<\/sup>\uff0e<\/p>\n

\u3000\uff16\u6b73\u672a\u6e80\u3060\u3068\u6d17\u53e3\u5264\u306f\u4f7f\u3044\u306b\u304f\u3044\u3067\u3059\u304b\u3089\uff0c\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u63a8\u5968\u3057\u3066\u3044\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u304c\uff0c\u3053\u306e\u3042\u305f\u308a\u306f\u7c73\u56fd\u306e\u30d5\u30ed\u30ea\u30c7\u30fc\u30b7\u30e7\u30f3\u306e\u5f71\u97ff\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\uff0e\u3069\u3093\u306a\u3046\u8755\u306b\u6709\u52b9\u306a\u306e\u304b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u304c\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u6d3b\u52d5\u7684\u306a\u3046\u8755\u3088\u308a\u3082\u5065\u5168\u306a\u6b6f\u306b\u52b9\u679c\u304c\u3042\u308b20\uff09<\/sup>\u3068\u3044\u3046\u3088\u3046\u306a\u5831\u544a\u3082\u898b\u3089\u308c\u307e\u3057\u305f\uff0e\u305f\u3060\uff0c\u3053\u308c\u3082\u7121\u52b9\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\uff0e\u3056\u3063\u304f\u308a\u3068\u307e\u3068\u3081\u308b\u3068\uff0c\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u308b\u5834\u9762\u306f\u300c\u3046\u8755\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u300d\u300c\u521d\u671f\u3046\u8755(\u8131\u7070\u7b49)\u306e\u6240\u898b\u304c\u307f\u3089\u308c\u308b\u300d\u300c\u77e5\u899a\u904e\u654f\u75c7\u72b6\u304c\u3042\u308b\u300d\u3068\u3044\u3046\u3068\u3053\u308d\u3067\u3057\u3087\u3046\u304b\uff0e\u3082\u3061\u308d\u3093\uff0c\u30d5\u30c3\u5316\u7269\u914d\u5408\u6b6f\u78e8\u5264\uff0c\u6d17\u53e3\u5264\u306a\u3069\u3068\u4f75\u7528\u3059\u308b\u3079\u304d\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u5b9f\u969b\u306b\u4f7f\u7528\u3057\u3066\u307f\u308b\u3068\u308f\u304b\u308b\u306e\u3067\u3059\u304c\uff0c\u6b6f\u9762\u3092\u3057\u3063\u304b\u308a\u4e7e\u71e5\u3055\u305b\u3066\u5857\u5e03\u3059\u308b\u3068\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u786c\u5316\u304c\u65e9\u304f\u8131\u96e2\u304c\u3042\u308a\u307e\u305b\u3093\uff0e\u5857\u5e03\u5f8c\u3082\u51fa\u6765\u308b\u3060\u3051\u4e7e\u71e5\u306b\u8fd1\u3044\u72b6\u614b\u304c\u6c42\u3081\u3089\u308c\u308b\u3068\u601d\u3044\u307e\u3059\uff0e\u307e\u305f\uff0c\u30ea\u30b9\u30af\u90e8\u4f4d\u3067\u3042\u308b\u5c0f\u7aa9\u88c2\u6e9d\u3084\u96a3\u63a5\u9762\u306b\u306f\uff0c\u3088\u304f\u5165\u308a\u3053\u3080\u3088\u3046\u306b\u4f55\u56de\u3082\u64e6\u308b\u3088\u3046\u306b\u5857\u5e03\u3057\u305f\u307b\u3046\u304c\u3088\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e\u3053\u306e\u3088\u3046\u306a\u64cd\u4f5c\u3092\u8003\u616e\u3059\u308b\u3068\uff0c\u5e7c\u5150\u306b\u4f7f\u7528\u3059\u308b\u3088\u308a\u3082\uff0c\u3042\u308b\u7a0b\u5ea6\u6307\u793a\u52d5\u4f5c\u306b\u5f93\u3046\u3053\u3068\u304c\u3067\u304d\u308b\u5e74\u9f62\u306e\u5c0f\u5150\u306b\u5bfe\u3057\u4f7f\u7528\u3059\u308b\u3079\u304d\u306a\u306e\u304b\u306a\u3068\u8003\u3048\u307e\u3059\uff0e<\/p>\n

(2)\u8cbb\u7528\u5bfe\u52b9\u679c\u306b\u3064\u3044\u3066<\/strong><\/p>\n

\u3000\u5b9f\u306f\uff0c\u52e4\u52d9\u5148\u306e\u5730\u57df\u306e\u691c\u8a3a\u4e8b\u696d\u306b\u53c2\u52a0\u3057\u3066\u3044\u305f\u6570\u5e74\u524d\u304b\u3089\uff0c\u3007\u6b73\u5150\u691c\u8a3a\u6642\u306a\u3069\u516c\u5171\u65bd\u8a2d\u3067\u884c\u308f\u308c\u3066\u3044\u308b\u30d5\u30c3\u5316\u7269\u5857\u5e03(9,000ppm\/\u7dbf\u7403\u5857\u5e03\u6cd5)\u306b\u3064\u3044\u3066\u61d0\u7591\u7684\u3067\u3057\u305f\uff0e\u6570\u5e74\u306b\uff11\u56de(\u5e74\u306b\u6570\u56de\u3067\u306f\u306a\u3044)\uff0c\u7121\u5f71\u706f\u306e\u306a\u3044\u6697\u3044\u53e3\u8154\u5185\u306b\u3061\u3087\u3093\u3061\u3087\u3093\u3068\u5857\u5e03\u3057\uff0c\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u5b9a\u3081\u3089\u308c\u305f\uff14\u5206\u9593\u306e\u6e7f\u6f64\u72b6\u614b\u304c\u5b88\u308c\u306a\u3044\u308f\u3051\u3067\u3059\uff0e\u6b6f\u79d1\u885b\u751f\u58eb\u306a\u3069\u306e\u4eba\u7684\u8cc7\u6e90(\u30b3\u30b9\u30c8)\u3092\u6295\u5165\u3057\u3066\uff0c\u5f97\u3089\u308c\u308b\u7d50\u679c\u306f\u3069\u306e\u7a0b\u5ea6\u306a\u306e\u3060\u308d\u3046\u304b\u30fb\u30fb\u30fb\u3068\uff0e\u8cbb\u7528\u5bfe\u52b9\u679c\u3082\u305d\u3046\u3067\u3059\u304c\uff0c\u75ab\u5b66\u7684\u306b\u3082\u3053\u308c\u306f\u6709\u52b9\u306a\u306e\u3060\u308d\u3046\u304b\u30fb\u30fb\u30fb\u3068\uff0e\u3053\u306e\u7dbf\u7403\u5857\u5e03\u6cd5\u306b\u3088\u308b\u30dd\u30d4\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u95a2\u3057\u3066\u306f\u306a\u304b\u306a\u304b\u96e3\u3057\u305d\u3046\u3060\u305e\uff0e\u306a\u3069\u3068\u8003\u3048\u3066\u3044\u307e\u3057\u305f\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u30dd\u30d4\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3064\u3044\u3066\u3082\u53b3\u3057\u3044\u7814\u7a76\u304c\u6563\u898b\u3055\u308c\u307e\u3057\u305f\uff0e\u65e5\u672c\u3067\u8cbb\u7528\u5bfe\u52b9\u679c\u3092\u7121\u8996\u3057\u305f\u904b\u7528\u304c\u3055\u308c\u308b\u3053\u3068\u304c\u306a\u3044\u3088\u3046\u7948\u308b\u3070\u304b\u308a\u3067\u3059\uff0e<\/p>\n

(3)\u3046\u8755\u7ba1\u7406\u306b\u3064\u3044\u3066<\/strong><\/p>\n

\u3000\u73fe\u5728\u306e\u6b6f\u79d1\u5065\u5eb7\u4fdd\u967a\u5236\u5ea6\u3067\u306fSPT\u3084P\u91cd\u9632\u306a\u3069\u6b6f\u8089\u708e\u3084\u6b6f\u5468\u708e\u306b\u5bfe\u3059\u308b\u30e1\u30a4\u30f3\u30c6\u30ca\u30f3\u30b9\u306f\u30ab\u30d0\u30fc\u51fa\u6765\u3066\u3044\u307e\u3059\u304c\uff0c\u3046\u8755\u306b\u3064\u3044\u3066\u306e\u30d5\u30a9\u30ed\u30fc\u306f\u306a\u304f\uff0c\u30d5\u30c3\u5316\u7269\u5857\u5e03\u306f16\u6b73\u672a\u6e80\u306e\u3046\u8755\u591a\u767a\u50be\u5411\u8005\u308465\u6b73\u4ee5\u4e0a\u306e\u6839\u9762\u3046\u8755\uff0c\u30a8\u30ca\u30e1\u30eb\u8cea\u3046\u8755\u306b\u9650\u3089\u308c\u3066\u3044\u307e\u3059\uff0e\u672c\u6765\uff0c\u300c\u3046\u8755\u304c\u591a\u767a\u3057\u3066\u3044\u308b\u304b\u3089\u300d\u300c\u6839\u9762\u521d\u671f\u3046\u8755\u304c\u767a\u751f\u3057\u3066\u3044\u308b\u304b\u3089\u300d\u300c\u521d\u671f\u30a8\u30ca\u30e1\u30eb\u8cea\u3046\u8755\u304c\u767a\u751f\u3057\u3066\u3044\u308b\u304b\u3089\u300d\u3067\u306f\u306a\u304f\u300c\u3046\u8755\u304c\u767a\u751f\u3057\u306a\u3044\u3088\u3046\u306b\u300d\u300c\u6839\u9762\u521d\u671f\u3046\u8755\u304c\u767a\u751f\u3057\u306a\u3044\u3088\u3046\u306b\u300d\u300c\u521d\u671f\u30a8\u30ca\u30e1\u30eb\u8cea\u3046\u8755\u304c\u767a\u751f\u3057\u306a\u3044\u3088\u3046\u306b\u300d\u30d5\u30c3\u5316\u7269\u5fdc\u7528\u3092\u5b9f\u65bd\u3059\u308b\u3079\u304d\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\uff0e<\/p>\n

\u3000\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3067\u306f2000\u5e74\u9803\u307e\u3067\u901a\u79f0\u300c\u30d5\u30c3\u7d20\u304a\u3070\u3055\u3093\u300d\u304c\u6bce\u9031\uff0c\u5c0f\u5b66\u6821\u306b\u3084\u3063\u3066\u304d\u3066\u6b6f\u78e8\u304d\u3092\u6559\u3048\u3066\u304f\u308c\u305f\u308a\uff0c\u30d5\u30c3\u5316\u7269\u96c6\u56e3\u6d17\u53e3\u3092\u5b9f\u65bd\u3057\u3066\u3044\u305f\u3068\u3044\u3046\u8a71\u3092\u805e\u3044\u305f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff0e\u6b6f\u79d1\u5148\u9032\u56fd\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3067\u3082\uff0c\u3046\u8755\u306e\u6e1b\u5c11\u30fb\u30d5\u30c3\u5316\u7269\u5165\u308a\u6b6f\u78e8\u5264\u306e\u666e\u53ca\u306a\u3069\u6642\u4ee3\u80cc\u666f\u306e\u5909\u5316\u306b\u3088\u308a\u30d5\u30c3\u5316\u7269\u96c6\u56e3\u6d17\u53e3\u306a\u3069\u306e\u516c\u8846\u885b\u751f\u7684\u5fdc\u7528\u304b\u3089\u30bb\u30eb\u30d5\u30b1\u30a2\u30fb\u6b6f\u79d1\u533b\u9662\u3067\u306e\u500b\u4eba\u30a2\u30d7\u30ed\u30fc\u30c1\u3078\u5909\u308f\u3063\u3066\u3044\u307e\u3059\uff0e\u3046\u8755\uff1d\u5207\u524a\u3067\u306f\u306a\u304f\u7ba1\u7406\u3059\u308b\u6642\u4ee3\u3067\u3059\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u4e88\u9632\u6b6f\u79d1\u81e8\u5e8a\u306b\u53d6\u308a\u5165\u308c\u3066\u307f\u3066\u306f\u3044\u304b\u304c\u3067\u3057\u3087\u3046\u304b\uff0e<\/p>\n

 <\/p>\n

\uff17\uff0eQ&A<\/strong><\/h2>\n

Q \u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u3069\u306e\u304f\u3089\u3044\u6614\u304b\u3089\u3042\u3063\u305f\u3082\u306e\u3067\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u4e00\u756a\u53e4\u3044\u6587\u732e\u306f1940\u5e74\u4ee3\u306e\u3082\u306e\u3067\u3057\u305f\uff0e\u65e5\u672c\u3067\u521d\u3081\u3066\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u767a\u58f2\u3055\u308c\u305f\u306e\u306f1981\u5e74\u306eF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u6700\u521d\u3067\u3059\uff0e<\/p>\n

Q \u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u5f8c\uff0c\u4ed6\u306e\u30d5\u30c3\u5316\u7269\u914d\u5408\u6b6f\u78e8\u5264\u3084\u6d17\u53e3\u5264\u306f\u4f7f\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u5857\u5e03\u5f8c24\u6642\u9593\u306f\u30d5\u30c3\u5316\u7269\u6b6f\u9762\u5857\u5e03(9,000ppm)\u306a\u3069\u4ed6\u306e\u30d5\u30c3\u5316\u7269\u51e6\u7f6e\u306f\u884c\u308f\u306a\u3044\u3088\u3046\u306b\u3057\u307e\u30597,8)<\/sup>\uff0e\u6b6f\u78e8\u5264\u3084\u6d17\u53e3\u5264\u306f\u6642\u9593\u3092\u958b\u3051\u3066\u4f7f\u7528\u53ef\u80fd\u3067\u3059\uff0e<\/p>\n

Q \u5857\u5e03\u5f8c\uff0c\u51fa\u3066\u304d\u305f\u553e\u6db2\u306f\u98f2\u307f\u8fbc\u3093\u3067\u3082\u5927\u4e08\u592b\u3067\u3059\u304b\uff1f\u5410\u304d\u51fa\u3059\u3079\u304d\u3067\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u98f2\u307f\u8fbc\u3093\u3067\u3082\u554f\u984c\u3042\u308a\u307e\u305b\u30931, 12-16\uff09<\/sup>\uff0e\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u591a\u304f\u306f\u6b6f\u306b\u4ed8\u7740\u3057\uff0c\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u553e\u6db2\u306b\u6eb6\u3051\u51fa\u3057\u3066\u3057\u307e\u3046\u3053\u3068\u306f\u8003\u3048\u306b\u304f\u3044\u3067\u3059\uff0e<\/p>\n

Q \u30a2\u30ec\u30eb\u30ae\u30fc\u304c\u3042\u308b\u60a3\u8005\u3055\u3093\u306b\u4f7f\u7528\u3057\u305f\u5834\u5408\uff0c\u3069\u3046\u306a\u308a\u307e\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u307e\u308c2)<\/sup>\u3067\u3059\u304c\uff0c\u30a2\u30ec\u30eb\u30ae\u30fc\u304c\u3042\u308b\u60a3\u8005\u3055\u3093\u306f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u5f8c\uff0c\u53e3\u8154\u7c98\u819c\u306e\u6d6e\u816b\u6027\u816b\u8139\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff0e\u307e\u305f\uff0c\u6f70\u760d\u3084\u53e3\u5185\u708e\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff0c\u307e\u308c\u306b\u6c17\u7ba1\u652f\u5598\u606f\u306e\u60a3\u8005\u3055\u3093\u306f\u5598\u606f\u767a\u4f5c\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u6d88\u5316\u7ba1\u306e\u904e\u654f\u306a\u60a3\u8005\u3055\u3093\u306f\u5e83\u7bc4\u56f2\u306b\u5857\u5e03\u3057\u305f\u5f8c\u306b\u80c3\u306e\u3080\u304b\u3064\u304d\u3084\u5614\u5410\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u30597)<\/sup>\uff0e<\/p>\n

Q \u306a\u305c\u7fa9\u6b6f\u88c5\u7740\u3084\u98f2\u98df\u7269\u306e\u6442\u53d6\uff0c\u6b6f\u78e8\u304d\u3092\u4e00\u5b9a\u6642\u9593\uff0c\u63a7\u3048\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u3067\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u7dbf\u7403\u5857\u5e03\u6cd5\u3068\u7570\u306a\u308a\uff0c\u6b6f\u9762\u306b\u786c\u5316\u3057\u4ed8\u7740\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u9577\u6642\u9593\u306e\u4f5c\u7528(\u30d5\u30c3\u5316\u7269\u306e\u30c1\u30e3\u30fc\u30b8)\u3092\u53ef\u80fd\u3068\u3057\u305f\u88fd\u5264\u3067\u3059\uff0e\u3067\u304d\u308b\u3060\u3051\u786c\u5316\u3055\u305b\uff0c\u6b6f\u9762\u306b\u4ed8\u7740\u3055\u305b\u305f\u3044\u306e\u3067\uff0c\u98f2\u98df\u7269\u306e\u6442\u53d6\u306f\u907f\u3051\u308b\u3079\u304d\u3067\u3059\uff0e\u307e\u305f\uff0c\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u786c\u5316\u3059\u308b\u524d\u306b\u7fa9\u6b6f\u3092\u88c5\u7740\u3057\u305f\u308a\uff0c\u6b6f\u78e8\u304d\u3092\u3057\u3066\u3057\u307e\u3046\u3068\uff0c\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u53d6\u308c\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\uff0e<\/p>\n

Q \u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u786c\u5316\u3059\u308b\u524d\u306b\u6b6f\u30d6\u30e9\u30b7\u3092\u4f7f\u7528\u3057\u3066\u56fa\u307e\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\uff0e<\/strong><\/p>\n

\u3000\u5b8c\u5168\u306b\u786c\u5316\u3059\u308b\u524d\u306b\u6b6f\u78e8\u304d\u3057\u3066\u3057\u307e\u3046\u3068\uff0c\u6bdb\u306e\u9593\u306b\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u304c\u5165\u3063\u3066\u56fa\u307e\u3063\u3066\u3057\u307e\u3044\u307e\u3059\uff0e\u6b6f\u30d6\u30e9\u30b7\u306e\u6bdb\u5148\u304c\u56fa\u307e\u3063\u3066\u3057\u307e\u3063\u305f\u5834\u5408\u306f\u30a8\u30bf\u30ce\u30fc\u30eb\u3067\u304d\u308c\u3044\u306b\u306a\u308a\u307e\u30597)<\/sup>\uff0e\u77f3\u9e78\u7b49\u3067\u306f\u30ad\u30ec\u30a4\u306b\u306a\u308a\u307e\u305b\u3093\uff0e<\/p>\n

Q \u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u524d\u306b\u6b6f\u9762\u6e05\u6383\u306f\u3059\u308b\u3079\u304d\u3067\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u30d5\u30c3\u5316\u7269\u5fdc\u7528\u306e\u524d\u306e\u6b6f\u9762\u6e05\u6383\u306f\u57fa\u672c\u7684\u306b\u4e0d\u8981\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff0e\u6e05\u6383\u81ea\u4f53\u306e\u52b9\u679c\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\uff0c\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u5bfe\u8c61\u306b\u306a\u3063\u3066\u3044\u308b\u7814\u7a76\u3067\u306f\uff0c\u30da\u30fc\u30b9\u30c8\u3067\u6b6f\u9762\u6e05\u6383\u3092\u3057\u3066\u304b\u3089\u5857\u5e03\u3057\u3066\u3044\u308b\u7814\u7a76\u304c\u591a\u3044\u3088\u3046\u3067\u3059\uff0e\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u4ed8\u7740\u30fb\u786c\u5316\u306e\u305f\u3081\u306b\u6b6f\u9762\u306e\u4e7e\u71e5\u304c\u6709\u52b9\u3067\u3042\u308b\u305f\u3081\uff0c\u3067\u304d\u308b\u3060\u3051\u6b6f\u9762\u6e05\u6383\u306f\u3057\u305f\u307b\u3046\u304c\u3088\u3044(\u5c11\u306a\u304f\u3068\u3082\u6b6f\u78e8\u304d\u306f\u3057\u305f\u307b\u3046\u304c\u3088\u3044)\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

Q \u4ed6\u306b\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u3069\u3093\u306a\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u500b\u4eba\u7684\u306bMedicom Duraflor\u00ae<\/sup> 5% Sodium Fluoride Varnish(\u65e5\u672c\u672a\u767a\u58f2)\uff0cPremier\u00ae<\/sup> Enamel Pro\u00ae<\/sup> Varnish(\u65e5\u672c\u672a\u767a\u58f2)\u306e\u4f7f\u7528\u7d4c\u9a13\u304c\u3042\u308a\u307e\u3059\uff0e\u73fe\u5728\uff0c\u65e5\u672c\u3067\u306f\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306fF\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3092\u542b\u3081\uff13\u5264\u3067\u3059\u304c\uff0c\u4eca\u5f8c\u3082\u4e0a\u8a18\u306e\u3088\u3046\u306a\u6d77\u5916\u3067\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u88fd\u54c1\u304c\u65e5\u672c\u3067\u8ca9\u58f2\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff0e<\/p>\n

Q \u30d5\u30c3\u5316\u30b8\u30a2\u30f3\u30df\u30f3\u9280\u3068\u306e\u4f7f\u3044\u5206\u3051\u306f\u3069\u306e\u3088\u3046\u306b\u3059\u308b\u3079\u304d\u3067\u3059\u304b\uff1f<\/strong><\/p>\n

\u3000\u3082\u3068\u3082\u3068\uff0c\u785d\u9178\u9280\u306e\u4ee3\u66ff\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305f\u7d4c\u7def\u304c\u3042\u308b\u3088\u3046\u306b\u30d5\u30c3\u5316\u30b8\u30a2\u30f3\u30df\u30f3\u9280\u3068\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306e\u52b9\u679c\u30fb\u52b9\u80fd\u306f\u4f3c\u3066\u3044\u307e\u3059\uff0e\u73fe\u5728\uff0c\u6839\u9762\u3046\u8755\u306b\u30d5\u30c3\u5316\u30b8\u30a2\u30f3\u30df\u30f3\u9280\u300c\u30b5\u30db\u30e9\u30a4\u30c9\u6db2\u6b6f\u79d1\u752838%\/48,400ppm\u300d\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\uff0c\u30d5\u30c3\u5316\u7269\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u3082\u6839\u9762\u3046\u8755\u306b\u6709\u52b9\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff0e\u30b5\u30db\u30e9\u30a4\u30c9\u306f\u3046\u8755\u3092\u9ed2\u5316\u3055\u305b\u307e\u3059\u304c\uff0c\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u306f\u3046\u8755\u3092\u9ed2\u5316\u3055\u305b\u307e\u305b\u3093\uff0e\u79c1\u306f\u5e7c\u3044\u3053\u308d\uff0c\u7236\u306b\u4e73\u524d\u6b6f\u306b\u30b5\u30db\u30e9\u30a4\u30c9\u3092\u5857\u5e03\u3055\u308c\u305f\u7d4c\u9a13\u304c\u3042\u308a\u307e\u3057\u3066\uff0c\u5c0f\u3055\u3044\u3053\u308d\u306f\u305d\u308c\u304c\u5acc\u3060\u3063\u305f\u3053\u3068\u3092\u899a\u3048\u3066\u3044\u307e\u3059\uff0e\u9ed2\u5316\u3057\u3066\u56f0\u308b\u90e8\u4f4d\u306b\u306f\u30d0\u30fc\u30cb\u30c3\u30b7\u30e5\u5857\u5e03\u3092\u691c\u8a0e\u3059\u308b\u3068\u3088\u3044\u3068\u601d\u3044\u307e\u3059\uff0e<\/p>\n

 <\/p>\n

\uff18\uff0e\u53c2\u8003\u6587\u732e<\/strong><\/h2>\n

1) Milgrom P, Taves DM, Kim AS, Watson GE, Horst JA. Pharmacokinetics of fluoride in toddlers after application of 5% sodium fluoride dental varnish. Pediatrics. 2014 Sep;134(3): e870-4.<\/p>\n

2\uff09\u30a4\u30ae\u30ea\u30b9\u653f\u5e9c\u30c7\u30b8\u30bf\u30eb\u30b5\u30fc\u30d3\u30b9 Guidance Chapter 9: Fluoride\u3000https:\/\/www.gov.uk\/government\/publications\/delivering-better-oral-health-an-evidence-based-toolkit-for-prevention\/chapter-9-fluoride<\/a>\u3000(Retrieved on April 17, 2022)<\/p>\n

3) \u65b0\u6d77\u7814\u5fd7 \u8c61\u7259\u8cea\u306b\u304a\u3088\u307c\u3059Fluoride Varnish\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066 \u53e3\u8154\u885b\u751f\u5b66\u4f1a\u8a8c1979, 29-2 P134-144<\/p>\n

4) 3M\u30af\u30ea\u30f3\u30d7\u30ed \u30db\u30ef\u30a4\u30c8 \u30d0\u30fc\u30cb\u30c3\u30b7\u30e5 F\u3000https:\/\/www.3mcompany.jp\/3M\/ja_JP\/dental-jp\/products\/preventive\/clinpro-white-varnish-f\/<\/a>\u3000(Retrieved on April 17, 2022)<\/p>\n

5) Koch G, Petersson LG. Fluoride content of enamel surface treated with a varnish containing sodium fluoride. Odontol Revy. 1972;23(4):437-46.<\/p>\n

6) \u53ef\u5150 \u745e\u592b\u3089 Fluoride Varnish\u306e\u30a8\u30ca\u30e1\u30eb\u8cea\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff\u306b\u3064\u3044\u3066-in vitro\u53e3\u8154\u885b\u751f\u5b66\u4f1a\u96d1\u8a8c1987, 37-3 P342-351<\/p>\n

7) Colgate Duraphat\u00ae https:\/\/www.colgateprofessional.com.au\/products\/products-list\/colgate-duraphat-varnish<\/a>\u3000(Retrieved on April 17, 2022)<\/p>\n

8) Lukomsky, E. H. “Fluorine Therapy for Exposed Dentin and Alveolar Atrophy’.” Journal of Dental Research 20.6 (1941): 649-659.<\/p>\n

9\uff09Hoyt, William H., and Basil G. Bibby. “Use of sodium fluoride for desensitizing dentin.” The Journal of the American Dental Association 30.17 (1943): 1372-1376.<\/p>\n

10\uff09\u539a\u751f\u52b4\u50cd\u7701 \u4fdd\u967a\u8a3a\u7642\u306b\u304a\u3051\u308b\u533b\u85ac\u54c1\u306e\u53d6\u6271\u3044\u306b\u3064\u3044\u3066\u3000https:\/\/www.mhlw.go.jp\/web\/t_doc?dataId=00tb0199&dataType=1&pageNo=1<\/a>\u3000(Retrieved on April 17, 2022)<\/p>\n

11) Lockner F, Twetman S, Stecks\u00e9n-Blicks C. Urinary fluoride excretion after application of fluoride varnish and use of fluoride toothpaste in young children. Int J Paediatr Dent. 2017 Nov;27(6):463-468.<\/p>\n

12) Twetman S, Stecks\u00e9n-Blicks C. Urinary Fluoride Excretion after a Single Application of Fluoride Varnish in Preschool Children. Oral Health Prev Dent. 2018;16(4):351-354.<\/p>\n

13) Ekstrand J, Koch G, Petersson LG. Plasma fluoride concentration and urinary fluoride excretion in children following application of the fluoride-containing varnish Duraphat. Caries Res. 1980;14(4):185-9.<\/p>\n

14)Milgrom P, Taves DM, Kim AS, Watson GE, Horst JA. Pharmacokinetics of fluoride in toddlers after application of 5% sodium fluoride dental varnish. Pediatrics. 2014 Sep;134(3):e870-4.<\/p>\n

15)Lockner F, Twetman S, Stecks\u00e9n-Blicks C. Urinary fluoride excretion after application of fluoride varnish and use of fluoride toothpaste in young children. Int J Paediatr Dent. 2017 Nov;27(6):463-468.<\/p>\n

16) Mascarenhas AK. Is fluoride varnish safe? : Validating the safety of fluoride varnish. J Am Dent Assoc. 2021 May;152(5):364-368.<\/p>\n

17\uff09Marinho VC, Worthington HV, Walsh T, Clarkson JE. Fluoride varnishes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. 2013 Jul 11;(7):CD002279.<\/p>\n

18\uff09Timms L, Deery C. Fluoride varnish and dental caries in preschoolers: a systematic review and meta-analysis. Evid Based Dent. 2020 Mar;21(1):18-19.<\/p>\n

19) \u7c73\u6e80\u6b63\u7f8e\u3089 \u65b0\u4e88\u9632\u6b6f\u79d1\u5b66\u7b2c\uff14\u7248 \u533b\u6b6f\u85ac\u51fa\u7248<\/p>\n

20) Oliveira BH, Salazar M, Carvalho DM, Falc\u00e3o A, Campos K, Nadanovsky P. Biannual fluoride varnish applications and caries incidence in preschoolers: a 24-month follow-up randomized placebo-controlled clinical trial. Caries Res. 2014;48(3):228-36.<\/p>\n

21) Agouropoulos A, Twetman S, Pandis N, Kavvadia K, Papagiannoulis L. Caries-preventive effectiveness of fluoride varnish as adjunct to oral health promotion and supervised tooth brushing in preschool children: a double-blind randomized controlled trial. J Dent. 2014 Oct;42(10):1277-83.<\/p>\n

22) Yu L, Yu X, Li Y, Yang F, Hong J, Qin D, Song G, Hua F. The additional benefit of professional fluoride application for children as an adjunct to regular fluoride toothpaste: a systematic review and meta-analysis. Clin Oral Investig. 2021 Jun;25(6):3409-3419.<\/p>\n

23) Anderson M, Dahll\u00f6f G, Soares FC, Grindefjord M. Impact of biannual treatment with fluoride varnish on tooth-surface-level caries progression in children aged 1-3 years. J Dent. 2017 Oct;65:83-88.<\/p>\n

24\uff09de Sousa FSO, Dos Santos APP, Nadanovsky P, Hujoel P, Cunha-Cruz J, de Oliveira BH. Fluoride Varnish and Dental Caries in Preschoolers: A Systematic Review and Meta-Analysis. Caries Res. 2019;53(5):502-513.<\/p>\n

25) Anderson M, Davidson T, Dahll\u00f6f G, Grindefjord M. Economic evaluation of an expanded caries-preventive program targeting toddlers in high-risk areas in Sweden. Acta Odontol Scand. 2019 May;77(4):303-309.<\/p>\n

26) Lin PY, Wang J, Chuang TY, Chang YM, Chang HJ, Chi LY. Association between population-based fluoride varnish application services and dental caries experience among schoolchildren in Taiwan. J Formos Med Assoc. 2021 Aug 2: S0929-6646(21)00347-8.<\/p>\n

27) Weyant RJ, Tracy SL, Anselmo TT, Beltr\u00e1n-Aguilar ED, Donly KJ, Frese WA, Hujoel PP, Iafolla T, Kohn W, Kumar J, Levy SM, Tinanoff N, Wright JT, Zero D, Aravamudhan K, Frantsve-Hawley J, Meyer DM; American Dental Association Council on Scientific Affairs Expert Panel on Topical Fluoride Caries Preventive Agents. Topical fluoride for caries prevention: executive summary of the updated clinical recommendations and supporting systematic review. J Am Dent Assoc. 2013 Nov;144(11):1279-91.<\/p>\n

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\uff19\uff0e\u304a\u3059\u3059\u3081<\/h2>\n

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